Illuminating Regulatory Guidance

Illuminating Nature

At the base level of creative practice, artists often reap inspiration from their surroundings. Writers might eavesdrop on a conversation in a coffee shop and then use it in a novel, and a composer might transform sounds from his urban environment into an orchestral work. In Kelly Lanphier’s case, working at the Aquarium of the Pacific in Long Beach, California, early on created a substantial i...

Illuminating Illumination

We introduce an active imaging method to measure scene illumination. The system implementation is divided into four steps. First, the system acquires two images: one is an ordinary image of the scene under ambient light and the other is a corresponding image in which light from the camera flash is added to the scene. Second, the image pair is analyzed to obtain an image that represents the scen...

Regulatory Guidance Documents on Adaptive Designs: An Industry Perspective

W. He et al. (eds.), Practical Considerations for Adaptive Trial Design and Implementation, Statistics for Biology and Health, DOI 10.1007/978-1-4939-1100-4_2, © Springer Science+Business Media New York 2014 Abstract Adaptive designs have the potential to be a transformative methodology in clinical drug development, but acceptance by regulatory agencies is a prerequisite for their broader adopt...

Request for regulatory guidance for cancer cachexia intervention trials

Clinical and Surgical Sciences, School of Clinical Sciences and Community Health, Royal Infirmary, University of Edinburgh, Edinburgh, UK; Biochemistry and Molecular Biology of Cancer, Faculty of Biology, University of Barcelona, Barcelona, Spain; Department of Oncology, University of Alberta, Edmonton, Alberta , Canada; Department of Geriatrics, Neurosciences, and Orthopedics, Catholic Univers...

Illuminating the Universe's Ignition